The University of British Columbia

Core Area(s): Behavioural Neuroscience

Research Interests
Exploring the basis of cognitive function and impulse control at a neural, neurochemical and molecular level using rodent analogues of human neuropsychological tests; emphasis on frontostriatal systems, goal-directed behaviour, serotonin, dopamine and noradrenaline.

Courses Taught
PSYC 361 Motivation, PSYC 304 Brain and Behaviour

Representative Publications
Winstanley CA, LaPlant Q , Theobald DE , Green TA, Bachtell RK , Perrotti LI , DiLeone RJ, Russo SJ, Garth WJ , Self DW, Nestler EJ (2007) "DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction." Journal of Neuroscience 27: 10497-507.

Winstanley CA, Eagle DM and Robbins TW (2006) “Behavioural models of impulsivity: translation between clinical and preclinical studies” Clinical Psychology Review (4):379-95.

Winstanley CA, Theobald DEH, Dalley JW, Cardinal RN and Robbins TW (2006) “Double dissociation between serotonergic and dopaminergic modulation of medial prefrontal and orbitofrontal cortex during a test of impulsive choice” Cerebral Cortex, 16: 106-14

Winstanley CA, Baunez C, Theobald DEH and Robbins TW (2005) “Lesions to the subthalamic nucleus decrease impulsive choice yet impair autoshaping in rats: the importance of the basal ganglia in Pavlovian conditioning and impulse control” European Journal of Neuroscience 11: 3107-16

Winstanley CA, Dalley, JW, Theobald DEH and Robbins TW (2005) “Interactions between serotonin and dopamine in the control of impulsive choice in rats: therapeutic implications for impulse control disorders” Neuropsychopharmacology 30: 669-82

Winstanley CA, Theobald DEH, Cardinal RN and Robbins TW (2004) “Contrasting roles of basolateral amygdala and orbitofrontal cortex in impulsive choice” Journal of Neuroscience 19: 4718-4722